› 2pes

X-ray diffraction
1.6Å resolution

Urate Oxidase in complex with tris-dipicolinate Lutetium

Released:
DOI: 10.2210/pdb2pes/pdb
PDB 2pes coloured by chain and viewed from the front.
PDB 2pes coloured by chain and viewed from the side.
PDB 2pes coloured by chain and viewed from the top.
Source organism: Aspergillus flavus
Primary publication:
A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction.
Pompidor G, Maury O, Vicat J, Kahn R
Acta Crystallogr. D Biol. Crystallogr. 66 762-9 (2010)
PMID: 20606256

Function and Biology Details

Reaction catalysed: 
Urate + O(2) + H(2)O = 5-hydroxyisourate + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uricase Chain: A
Molecule details ›
Chain: A
Length: 295 amino acids
Theoretical weight: 33.5 KDa
Source organism: Aspergillus flavus
UniProt:
  • Canonical: Q00511 (Residues: 2-296; Coverage: 98%)
Gene names: Uox, uaZ
Sequence domains: Uricase
Structure domains: Urate Oxidase;

Ligands and Environments

3 bound ligands:
Ligand LU 3 x LU
Ligand AZA 1 x AZA
Ligand PDC 6 x PDC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: I222
Unit cell:
a: 79.55Å b: 95.32Å c: 104.33Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.195

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Citations

11 citation in other articles

Crystal structure of pb9, the distal tail protein of bacteriophage T5: a conserved structural motif among all siphophages.
Flayhan et al. (2014)
10 more