X-ray diffraction
1.6Å resolution

Urate Oxidase in complex with tris-dipicolinate Lutetium

Source organism: Aspergillus flavus
Primary publication:
A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction.
Acta Crystallogr. D Biol. Crystallogr. 66 762-9 (2010)
PMID: 20606256

Function and Biology Details

Reaction catalysed:
Urate + O(2) + H(2)O = 5-hydroxyisourate + H(2)O(2)
Biochemical function:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Uricase Chain: A
Molecule details ›
Chain: A
Length: 295 amino acids
Theoretical weight: 33.5 KDa
Source organism: Aspergillus flavus
  • Canonical: Q00511 (Residues: 2-296; Coverage: 98%)
Gene names: Uox, uaZ
Sequence domains: Uricase
Structure domains: Urate Oxidase;

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: I222
Unit cell:
a: 79.55Å b: 95.32Å c: 104.33Å
α: 90° β: 90° γ: 90°
R R work R free
0.18 0.179 0.195