PDBe 2pcu

X-ray diffraction
1.6Å resolution

Human carboxypeptidase A4 in complex with a cleaved hexapeptide.

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Carboxypeptidase A4 Chain: A
Molecule details ›
Chain: A
Length: 305 amino acids
Theoretical weight: 34.23 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: NEW Q9UI42 (Residues: 116-420; Coverage: 75%)
Gene names: CPA3, CPA4, UNQ694/PRO1339
Sequence domains: Zinc carboxypeptidase
Structure domains: Zn peptidases
peptide Chain: B
Molecule details ›
Chain: B
Length: 5 amino acids
Theoretical weight: 633 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 50.304Å b: 72.494Å c: 81.575Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.159 0.159 0.176
Expression systems:
  • Komagataella pastoris
  • Not provided