› 2p8c

X-ray diffraction
2Å resolution

Crystal structure of N-succinyl Arg/Lys racemase from Bacillus cereus ATCC 14579 complexed with N-succinyl Arg.

Released:
DOI: 10.2210/pdb2p8c/pdb
PDB entry 2p8c coloured by chain, front view.
PDB entry 2p8c coloured by chain, side view.
PDB entry 2p8c coloured by chain, top view.
Source organism: Bacillus cereus ATCC 14579
Primary publication:
Prediction and assignment of function for a divergent N-succinyl amino acid racemase.
Song L, Kalyanaraman C, Fedorov AA, Fedorov EV, Glasner ME, Brown S, Imker HJ, Babbitt PC, Almo SC, Jacobson MP, Gerlt JA
Nat Chem Biol 3 486-91 (2007)
PMID: 17603539

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182546 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N-succinyl-L-Arg/Lys racemase Chain: A
Molecule details ›
Chain: A
Length: 369 amino acids
Theoretical weight: 41 KDa
Source organism: Bacillus cereus ATCC 14579
Expression system: Escherichia coli
UniProt:
  • Canonical: Q81IL5 (Residues: 1-369; Coverage: 100%)
Gene name: BC_0371
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand SUG 1 x SUG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: I422
Unit cell:
a: 137.339Å b: 137.339Å c: 87.85Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.18 0.199
Expression system: Escherichia coli

Quick links

Citations

16 review citations

Enzyme Function Initiative-Enzyme Similarity Tool (EFI-EST): A web tool for generating protein sequence similarity networks.
Gerlt et al. (2015)
15 more

1 mention without citation

Leveraging structure for enzyme function prediction: methods, opportunities, and challenges.
Jacobson et al. (2014)