X-ray diffraction
2.2Å resolution

Crystal structure of monoclinic form of genomically encoded fosfomycin resistance protein, FosX, from Listeria monocytogenes at pH 5.75


Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo hexamer
Entry contents:
1 distinct polypeptide molecule
Fosfomycin resistance protein FosX Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 133 amino acids
Theoretical weight: 15.59 KDa
Source organism: Listeria monocytogenes EGD-e
Expression system: Escherichia coli
  • Canonical: Q8Y6I2 (Residues: 1-133; Coverage: 100%)
Gene names: fosX, lmo1702
Sequence domains: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
Structure domains: 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR591
Spacegroup: C2
Unit cell:
a: 168.779Å b: 70.697Å c: 86.974Å
α: 90° β: 113.98° γ: 90°
R R work R free
0.229 0.229 0.267
Expression system: Escherichia coli