› 2p6t

X-ray diffraction
2.9Å resolution

CRYSTAL STRUCTURE OF TRANSCRIPTIONAL REGULATOR NMB0573 and L-LEUCINE COMPLEX FROM NEISSERIA MENINGITIDIS

Released:
DOI: 10.2210/pdb2p6t/pdb
PDB entry 2p6t coloured by chain, front view.
PDB entry 2p6t coloured by chain, side view.
PDB entry 2p6t coloured by chain, top view.
Source organism: Neisseria meningitidis MC58
Primary publication:
The structure and transcriptional analysis of a global regulator from Neisseria meningitidis.
Ren J, Sainsbury S, Combs SE, Capper RG, Jordan PW, Berrow NS, Stammers DK, Saunders NJ, Owens RJ
J Biol Chem 282 14655-64 (2007)
PMID: 17374605

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191724 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH asnC-type domain-containing protein Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 162 amino acids
Theoretical weight: 18.29 KDa
Source organism: Neisseria meningitidis MC58
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9K0L9 (Residues: 28-187; Coverage: 86%)
Gene name: NMB0573
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand LEU 8 x LEU
Ligand GOL 6 x GOL
Ligand CA 11 x CA
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21
Unit cell:
a: 65.389Å b: 149.771Å c: 77.845Å
α: 90° β: 105.68° γ: 90°
R-values:
R R work R free
0.239 0.235 0.3
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Metabolism and virulence in Neisseria meningitidis.
Schoen et al. (2014)
5 more