PDBe 2ouh

X-ray diffraction
2.4Å resolution

Crystal structure of the Thrombospondin-1 N-terminal domain in complex with fractionated Heparin DP10

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thrombospondin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 251 amino acids
Theoretical weight: 27.56 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Best match: P07996 (Residues: 19-257)
Gene names: THBS1, TSP, TSP1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 40.316Å b: 41.069Å c: 241.779Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.257 0.253 0.296
Expression system: Drosophila melanogaster