› 2osz

X-ray diffraction
2.85Å resolution

Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding

Released:
DOI: 10.2210/pdb2osz/pdb
PDB entry 2osz coloured by chain, front view.
PDB entry 2osz coloured by chain, side view.
PDB entry 2osz coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding.
Melcák I, Hoelz A, Blobel G
Science 315 1729-32 (2007)
PMID: 17379812

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159741 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin p58/p45 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 93 amino acids
Theoretical weight: 10.78 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P70581 (Residues: 326-415; Coverage: 15%)
Gene names: Nup58, Nupl1
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P4322
Unit cell:
a: 92.705Å b: 92.705Å c: 169.553Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.25 0.288
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Crossing the nuclear envelope: hierarchical regulation of nucleocytoplasmic transport.
Terry et al. (2007)
18 more

3 mentions without citation

The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution.
Ulrich et al. (2014)
2 more