X-ray diffraction
1.5Å resolution

Thermotoga maritima thymidine kinase 1 like enzyme in complex with TP4A


Function and Biology Details

Reaction catalysed:
ATP + thymidine = ADP + thymidine 5'-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Thymidine kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 184 amino acids
Theoretical weight: 20.68 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
  • Canonical: Q9WYN2 (Residues: 1-184; Coverage: 100%)
Gene names: TM_0401, tdk
Sequence domains: Thymidine kinase
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: C2
Unit cell:
a: 102.55Å b: 59.63Å c: 61.44Å
α: 90° β: 103.11° γ: 90°
R R work R free
0.173 0.169 0.208
Expression system: Escherichia coli