2of5

X-ray diffraction
3.2Å resolution

Oligomeric Death Domain complex

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Death domain-containing protein CRADD Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 114 amino acids
Theoretical weight: 13.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P78560 (Residues: 94-199; Coverage: 53%)
Gene names: CRADD, RAIDD
Structure domains: Death Domain, Fas
PIDD-CC Chains: H, I, J, K, L
Molecule details ›
Chains: H, I, J, K, L
Length: 118 amino acids
Theoretical weight: 13.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HB75 (Residues: 778-883; Coverage: 12%)
Gene names: LRDD, PIDD, PIDD1
Structure domains: Death Domain, Fas

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P65
Unit cell:
a: 138.4Å b: 138.4Å c: 207.5Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.236 0.236 0.275
Expression system: Escherichia coli BL21(DE3)