X-ray diffraction
1.5Å resolution

Crystal Structure of the Catalytic Domain of Human Protein Tyrosine Phosphatase non-receptor Type 18


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Tyrosine-protein phosphatase non-receptor type 18 Chain: A
Molecule details ›
Chain: A
Length: 303 amino acids
Theoretical weight: 34.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q99952 (Residues: 6-299; Coverage: 64%)
Gene names: BDP1, PTPN18
Sequence domains: Protein-tyrosine phosphatase
Structure domains: Protein tyrosine phosphatase superfamily

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 46.338Å b: 63.763Å c: 48.992Å
α: 90° β: 102.64° γ: 90°
R R work R free
0.156 0.154 0.184
Expression system: Escherichia coli