› 2o4f

X-ray diffraction
1.5Å resolution

Structure of a parallel-stranded guanine tetraplex crystallised with monovalent ions

Released:
DOI: 10.2210/pdb2o4f/pdb
PDB entry 2o4f coloured by chain, front view.
PDB entry 2o4f coloured by chain, side view.
PDB entry 2o4f coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure of a d(TGGGGT) quadruplex crystallized in the presence of Li+ ions.
Creze C, Rinaldi B, Haser R, Bouvet P, Gouet P
Acta Crystallogr D Biol Crystallogr 63 682-8 (2007)
PMID: 17505106

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115699 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*TP*GP*GP*GP*GP*T)-3' Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 6 nucleotides
Theoretical weight: 1.88 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand NA 7 x NA
Ligand LI 1 x LI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P21
Unit cell:
a: 28.92Å b: 57.37Å c: 35.92Å
α: 90° β: 108° γ: 90°
R-values:
R R work R free
0.206 0.204 0.257
Expression system: Not provided

Quick links

Citations

3 review citations

The application of DNA and RNA G-quadruplexes to therapeutic medicines.
Collie et al. (2011)
2 more

1 mention without citation

Shape matters: size-exclusion HPLC for the study of nucleic acid structural polymorphism.
Largy et al. (2014)