PDBe 2o0l

X-ray diffraction
1.99Å resolution

Human spermidine synthase

Released:
Source organism: Homo sapiens
Primary publication:
Structure and mechanism of spermidine synthases.
Biochemistry 46 8331-9 (2007)
PMID: 17585781

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spermidine synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 304 amino acids
Theoretical weight: 34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P19623 (Residues: 1-302; Coverage: 100%)
Gene names: SPS1, SRM, SRML1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 58.323Å b: 60.593Å c: 86.667Å
α: 90° β: 108.96° γ: 90°
R-values:
R R work R free
0.209 0.206 0.268
Expression system: Escherichia coli