2nvh

X-ray diffraction
1.53Å resolution

Determination of Solvent Content in Cavities in Interleukin-1 Using Experimentally-Phased Electron Density

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-1 beta Chain: A
Molecule details ›
Chain: A
Length: 153 amino acids
Theoretical weight: 17.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01584 (Residues: 117-269; Coverage: 57%)
Gene names: IL1B, IL1F2
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P43
Unit cell:
a: 54.506Å b: 54.506Å c: 75.359Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 not available not available
Expression system: Escherichia coli