2no2

X-ray diffraction
2.8Å resolution

Crystal structure of the DLLRKN-containing coiled-coil domain of Huntingtin-interacting protein 1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Huntingtin-interacting protein 1 Chain: A
Molecule details ›
Chain: A
Length: 107 amino acids
Theoretical weight: 12.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00291 (Residues: 482-586; Coverage: 10%)
Gene name: HIP1
Sequence domains: Clathrin-binding domain of Huntingtin-interacting protein 1
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P42212
Unit cell:
a: 54.2Å b: 54.2Å c: 152.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.403 0.286 0.313
Expression system: Escherichia coli