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Crystal structure of the Ets1 dimer DNA complex.

Source organism: Homo sapiens
Biochemical function: sequence-specific DNA binding
Biological process: regulation of transcription by RNA polymerase II
Cellular component: not assigned

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF00178
Domain description: Ets-domain
Occurring in:
  1. Protein C-ets-1
The deposited structure of PDB entry 2nny contains 2 copies of Pfam domain PF00178 (Ets-domain) in Protein C-ets-1. Showing 1 copy in chain C [auth A].

InterPro InterPro annotations
IPR000418
Domain description: Ets domain
Occurring in:
  1. Protein C-ets-1
IPR036390
Domain description: Winged helix DNA-binding domain superfamily
Occurring in:
  1. Protein C-ets-1
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. Protein C-ets-1
IPR046328
Domain description: ETS family
Occurring in:
  1. Protein C-ets-1
IPR045688
Domain description: Ets1, N-terminal flanking region of Ets domain
Occurring in:
  1. Protein C-ets-1

Structure domain

CATH CATH domain
1.10.10.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Occurring in:
  1. Protein C-ets-1
The deposited structure of PDB entry 2nny contains 2 copies of CATH domain 1.10.10.10 (Arc Repressor Mutant, subunit A) in Protein C-ets-1. Showing 1 copy in chain C [auth A].

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