› 2nms

X-ray diffraction
2.6Å resolution

The Crystal Structure of the Extracellular Domain of the Inhibitor Receptor Expressed on Myeloid Cells IREM-1

Released:
DOI: 10.2210/pdb2nms/pdb
PDB entry 2nms coloured by chain, front view.
PDB entry 2nms coloured by chain, side view.
PDB entry 2nms coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The crystal structure of the extracellular domain of the inhibitor receptor expressed on myeloid cells IREM-1.
Márquez JA, Galfré E, Dupeux F, Flot D, Moran O, Dimasi N
J Mol Biol 367 310-8 (2007)
PMID: 17275839

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186213 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CMRF35-like molecule 1 Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8TDQ1 (Residues: 20-140; Coverage: 45%)
Gene names: CD300F, CD300LF, CLM1, IGSF13, IREM1, NKIR, UNQ3105/PRO10111
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P3121
Unit cell:
a: 54.23Å b: 54.23Å c: 72.01Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.218 0.218 0.255
Expression system: Escherichia coli

Quick links

Citations

4 review citations

The CD300 molecules: an emerging family of regulators of the immune system.
Borrego F. (2013)
3 more

5 mentions without citation

Two-Dimensional Nanomaterials beyond Graphene for Biomedical Applications.
Derakhshi et al. (2022)
4 more