2ndj

Solution NMR

Structural Basis for KCNE3 and Estrogen Modulation of the KCNQ1 Channel

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium voltage-gated channel subfamily E member 3 Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y6H6 (Residues: 1-103; Coverage: 100%)
Gene name: KCNE3

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 40%
Refinement method: DGSA-distance geometry simulated annealing, molecular dynamics
Chemical shifts: BMR16621  
Expression system: Escherichia coli BL21(DE3)