› 2ncw

Solution NMR

NMR structure of WWWKYE21 structure in LPS micelles

Released:
DOI: 10.2210/pdb2ncw/pdb
PDB entry 2ncw coloured by chain, ensemble of 20 models, front view.
PDB entry 2ncw coloured by chain, ensemble of 20 models, side view.
PDB entry 2ncw coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Tryptophan end-tagging for promoted lipopolysaccharide interactions and anti-inflammatory effects.
Singh S, Datta A, Schmidtchen A, Bhunia A, Malmsten M
Sci Rep 7 212 (2017)
PMID: 28303012

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138704 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heparin cofactor 2 Chain: A
Molecule details ›
Chain: A
Length: 24 amino acids
Theoretical weight: 3.31 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05546 (Residues: 189-212; Coverage: 5%)
Gene names: HCF2, SERPIND1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 43%
Refinement method: distance geometry
Expression system: Not provided

Quick links

Citations

3 review citations

Anti-Inflammatory Function of Plant-Derived Bioactive Peptides: A Review.
Liu et al. (2022)
2 more

1 mention without citation

Tryptophan end-tagging for promoted lipopolysaccharide interactions and anti-inflammatory effects.
Singh et al. (2017)