2nbv

Solution NMR

Solution structure of the Rpn13 Pru domain engaging the hPLIC2 UBL domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proteasomal ubiquitin receptor ADRM1 Chain: A
Molecule details ›
Chain: A
Length: 150 amino acids
Theoretical weight: 16.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16186 (Residues: 1-150; Coverage: 37%)
Gene names: ADRM1, GP110
Sequence domains: Proteasome complex subunit Rpn13 ubiquitin receptor
Structure domains: Proteasomal ubiquitin receptor Rpn13/ADRM1
Ubiquilin-2 Chain: B
Molecule details ›
Chain: B
Length: 78 amino acids
Theoretical weight: 8.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UHD9 (Residues: 26-103; Coverage: 13%)
Gene names: HRIHFB2157, N4BP4, PLIC2, UBQLN2
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 46%
Refinement method: simulated annealing
Chemical shifts: BMR25995  
Expression system: Escherichia coli