PDBe 2nb1

Solution NMR

P63/p73 hetero-tetramerisation domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tumor protein 63 Chains: A, C
Molecule details ›
Chains: A, C
Length: 60 amino acids
Theoretical weight: 7.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9H3D4 (Residues: 397-455; Coverage: 9%)
Gene names: KET, P63, P73H, P73L, TP63, TP73L
Tumor protein p73 Chains: B, D
Molecule details ›
Chains: B, D
Length: 50 amino acids
Theoretical weight: 6.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O15350 (Residues: 351-398; Coverage: 8%)
Gene names: P73, TP73

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: molecular dynamics
Chemical shifts: BMR25958  
Expression system: Escherichia coli BL21