2n7r

Solution NMR

Structure of the transmembrane domain of human nicastrin in DPC micelles

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187681 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nicastrin Chain: A
Molecule details ›
Chain: A
Length: 54 amino acids
Theoretical weight: 5.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q92542 (Residues: 664-709; Coverage: 7%)
Gene names: KIAA0253, NCSTN, UNQ1874/PRO4317

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 63%
Refinement method: simulated annealing
Expression system: Escherichia coli