2n73

Solution NMR

Function and Biology Details

Reaction catalysed:
ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Golgi resident protein GCP60, N-terminally processed Chain: A
Molecule details ›
Chain: A
Length: 69 amino acids
Theoretical weight: 8.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H3P7 (Residues: 241-308; Coverage: 13%)
Gene names: ACBD3, GCP60, GOCAP1, GOLPH1
Phosphatidylinositol 4-kinase beta Chain: B
Molecule details ›
Chain: B
Length: 80 amino acids
Theoretical weight: 8.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UBF8 (Residues: 1-68; Coverage: 8%)
Gene names: PI4KB, PIK4CB

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: simulated annealing, molecular dynamics
Chemical shifts: BMR25791  
Expression system: Escherichia coli