2n5m

Solution NMR

Unveiling the structural determinants of KIAA0323 binding preference for NEDD8

Released:
Source organism: Homo sapiens
Entry authors: Santonico E, Nepravishta R, Mattioni A, Valentini E, Mandaliti W, Procopio R, Iannuccelli M, Castagnoli L, Polo S, Paci M, Cesareni G

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein KHNYN Chain: A
Molecule details ›
Chain: A
Length: 52 amino acids
Theoretical weight: 6.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15037 (Residues: 627-678; Coverage: 8%)
Gene names: KHNYN, KIAA0323

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 29%
Refinement method: simulated annealing
Chemical shifts: BMR25722  
Expression system: Escherichia coli