2n2c

Solution NMR

NMR Structure of TDP-43 prion-like hydrophobic helix in DPC

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TAR DNA-binding protein 43 Chain: A
Molecule details ›
Chain: A
Length: 43 amino acids
Theoretical weight: 4.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q13148 (Residues: 307-349; Coverage: 10%)
Gene names: TARDBP, TDP43

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 59%
Refinement method: molecular dynamics
Chemical shifts: BMR25595  
Expression system: Escherichia coli BL21