Solution NMR

Solution structure of hnRNP C RRM in complex with 5'-AUUUUUC-3' RNA


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Heterogeneous nuclear ribonucleoproteins C1/C2 Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 11.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P07910 (Residues: 2-106; Coverage: 34%)
Gene names: HNRNPC, HNRPC
Sequence domains: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Structure domains: Alpha-Beta Plaits
5'-R(*AP*UP*UP*UP*UP*UP*C)-3' Chain: B
Molecule details ›
Chain: B
Length: 7 nucleotides
Theoretical weight: 2.12 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: simulated annealing, torsion angle dynamics
Chemical shifts: BMR25436  
Expression systems:
  • Escherichia coli
  • Not provided