Solution NMR

Solution NMR structure of MAVS CARD

Source organism: Homo sapiens
Primary publication:
Structure determination of helical filaments by solid-state NMR spectroscopy.
Proc. Natl. Acad. Sci. U.S.A. 113 E272-81 (2016)
PMID: 26733681

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Mitochondrial antiviral-signaling protein Chain: A
Molecule details ›
Chain: A
Length: 102 amino acids
Theoretical weight: 11.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q7Z434 (Residues: 1-100; Coverage: 19%)
Gene names: IPS1, KIAA1271, MAVS, VISA
Sequence domains: Caspase recruitment domain
Structure domains: Death Domain, Fas

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: simulated annealing
Chemical shifts: BMR25109  
Expression system: Escherichia coli