› 2mrn

Solution NMR

Structure of truncated EcMazE

Released:
DOI: 10.2210/pdb2mrn/pdb
PDB entry 2mrn coloured by chain, ensemble of 20 models, front view.
PDB entry 2mrn coloured by chain, ensemble of 20 models, side view.
PDB entry 2mrn coloured by chain, ensemble of 20 models, top view.
Source organism: Escherichia coli K-12
Primary publication:
Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding.
Zorzini V, Buts L, Schrank E, Sterckx YG, Respondek M, Engelberg-Kulka H, Loris R, Zangger K, van Nuland NA
Nucleic Acids Res 43 1241-56 (2015)
PMID: 25564525

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142414 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Antitoxin MazE Chains: A, B
Molecule details ›
Chains: A, B
Length: 67 amino acids
Theoretical weight: 7.68 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P0AE72 (Residues: 2-50; Coverage: 60%)
Gene names: JW2754, b2783, chpAI, chpR, mazE
Sequence domains: Antidote-toxin recognition MazE, bacterial antitoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 47%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Keeping the Wolves at Bay: Antitoxins of Prokaryotic Type II Toxin-Antitoxin Systems.
Chan et al. (2016)
2 more

2 mentions without citation

Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding.
Zorzini et al. (2015)
1 more