2mq6

Solution NMR

Solution structure of Y125F mutant of eRF1 N-domain

Released:
Source organism: Homo sapiens
Entry authors: Pillay S, Li Y, Wong L, Pervushin K

Function and Biology Details

Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-158631 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic peptide chain release factor subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 15.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P62495 (Residues: 1-142; Coverage: 33%)
Gene names: ERF1, ETF1, RF1, SUP45L1
Sequence domains: eRF1 domain 1
Structure domains: eRF1 domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 81%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli