› 2miy

Solution NMR

Solution NMR structure of a preQ1 Class II riboswitch from Streptococcus pneumoniae

Released:
DOI: 10.2210/pdb2miy/pdb
PDB entry 2miy coloured by chain, ensemble of 18 models, front view.
PDB entry 2miy coloured by chain, ensemble of 18 models, side view.
PDB entry 2miy coloured by chain, ensemble of 18 models, top view.
Source organism: Streptococcus pneumoniae
Primary publication:
Structural determinants for ligand capture by a class II preQ1 riboswitch.
Kang M, Eichhorn CD, Feigon J
Proc. Natl. Acad. Sci. U.S.A. 111 E663-71 (2014)
PMID: 24469808

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195898 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA_(59-MER) Chain: A
Molecule details ›
Chain: A
Length: 59 nucleotides
Theoretical weight: 18.9 KDa
Source organism: Streptococcus pneumoniae
Expression system: Not provided
Sequence domains: preQ1-II (pre queuosine) riboswitch

Ligands and Environments

1 bound ligand:
Ligand PRF 1 x PRF
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 70%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

9 review citations

Progress and challenges for chemical probing of RNA structure inside living cells.
Kubota et al. (2015)
8 more

10 mentions without citation

Structure and function of preQ1 riboswitches.
Eichhorn et al. (2014)
9 more