› 2m52

Solution NMR

NMR Structure of the third RNA Recognition Motif (RRM) of U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2

Released:
DOI: 10.2210/pdb2m52/pdb
PDB entry 2m52 coloured by chain, ensemble of 20 models, front view.
PDB entry 2m52 coloured by chain, ensemble of 20 models, side view.
PDB entry 2m52 coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Entry authors: Dutta SK, Serrano P, Geralt M, Wuthrich K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150727 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Splicing factor U2AF 65 kDa subunit Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 12.03 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P26369 (Residues: 371-475; Coverage: 22%)
Gene names: U2af2, U2af65
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21

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