Solution NMR

Characterization of a Novel Alpha4/6-Conotoxin TxIC from Conus textile that Potently Blocks alpha3beta4 Nicotinic Acetylcholine Receptors


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Alpha-conotoxin Li1.12 Chain: A
Molecule details ›
Chain: A
Length: 16 amino acids
Theoretical weight: 1.49 KDa
Source organism: Conus lividus
Expression system: Not provided
  • Canonical: H9N3R7 (Residues: 16-30; Coverage: 48%)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 48%
Refinement method: simulated annealing
Chemical shifts: BMR18964  
Expression system: Not provided