PDBe 2m1k

Solution NMR

Interaction of Human S100A6 (C3S) with V domain of Receptor for Advanced Glycation End products (RAGE)

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein S100-A6 Chains: B, D
Molecule details ›
Chains: B, D
Length: 90 amino acids
Theoretical weight: 10.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P06703 (Residues: 1-90; Coverage: 100%)
Gene names: CACY, S100A6
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand
Advanced glycosylation end product-specific receptor Chains: A, C
Molecule details ›
Chains: A, C
Length: 101 amino acids
Theoretical weight: 11.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15109 (Residues: 23-121; Coverage: 26%)
Gene names: AGER, RAGE
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 8%
Refinement method: simulated annealing
Chemical shifts: BMR18868  
Expression system: Escherichia coli BL21(DE3)