› 2luu

Solution NMR

NMR solution structure of midkine-b, mdkb

Released:
DOI: 10.2210/pdb2luu/pdb
PDB entry 2luu coloured by chain, ensemble of 10 models, front view.
PDB entry 2luu coloured by chain, ensemble of 10 models, side view.
PDB entry 2luu coloured by chain, ensemble of 10 models, top view.
Source organism: Danio rerio
Primary publication:
Structure-function analysis of full-length midkine reveals novel residues important for heparin binding and zebrafish embryogenesis.
Lim J, Yao S, Graf M, Winkler C, Yang D
Biochem J 451 407-15 (2013)
PMID: 23418741

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190105 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Midkine Chain: A
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 14.02 KDa
Source organism: Danio rerio
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9DDG2 (Residues: 22-147; Coverage: 100%)
Gene names: cb518, fb79b05, fj33b02, fj48a12, mdk, mdk2, mdkb, plei2, wu:fb79b05, wu:fj33b02, wu:fj48a12
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 75%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Structure and function of midkine as the basis of its pharmacological effects.
Muramatsu T. (2014)
5 more