Solution NMR

LC3B OPTN-LIR Ptot complex structure


Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Microtubule-associated proteins 1A/1B light chain 3B Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9GZQ8 (Residues: 5-119; Coverage: 92%)
Gene names: MAP1ALC3, MAP1LC3B
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Optineurin Chain: B
Molecule details ›
Chain: B
Length: 17 amino acids
Theoretical weight: 2.25 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q96CV9 (Residues: 169-185; Coverage: 3%)
Gene names: FIP2, GLC1E, HIP7, HYPL, NRP, OPTN

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: restrained energy refinement
Chemical shifts: BMR18518  
Expression systems:
  • Escherichia coli
  • Not provided