› 2lsy

Solution NMR

Structure of the C-terminal domain from human REV1

Released:
DOI: 10.2210/pdb2lsy/pdb
PDB entry 2lsy coloured by chain, ensemble of 20 models, front view.
PDB entry 2lsy coloured by chain, ensemble of 20 models, side view.
PDB entry 2lsy coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase η.
Pozhidaeva A, Pustovalova Y, D'Souza S, Bezsonova I, Walker GC, Korzhnev DM
Biochemistry 51 5506-20 (2012)
PMID: 22691049

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193690 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA repair protein REV1 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 11.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UBZ9 (Residues: 1158-1251; Coverage: 8%)
Gene names: REV1, REV1L
Sequence domains: DNA repair protein REV1 C-terminal domain
Structure domains: DNA repair protein Rev1, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

15 review citations

Translesion DNA synthesis and mutagenesis in eukaryotes.
Sale JE. (2013)
14 more

9 mentions without citation

An overview of Y-Family DNA polymerases and a case study of human DNA polymerase η.
Yang W. (2014)
8 more