› 2lll

Solution NMR

Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A

Released:
DOI: 10.2210/pdb2lll/pdb
PDB entry 2lll coloured by chain, ensemble of 20 models, front view.
PDB entry 2lll coloured by chain, ensemble of 20 models, side view.
PDB entry 2lll coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Lemak A, Yee A, Houliston S, Garcia M, Xu C, Min J, Montelione GT, Arrowsmith C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC), Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169872 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lamin-B2 Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q03252 (Residues: 469-589; Coverage: 20%)
Gene names: LMN2, LMNB2
Sequence domains: Lamin Tail Domain
Structure domains: Lamin Tail domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 87%
Refinement method: restrained molecular dynamics
Expression system: Escherichia coli

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