2lf8

Solution NMR

Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to R458

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor ETV6 Chain: A
Molecule details ›
Chain: A
Length: 128 amino acids
Theoretical weight: 15.57 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P97360 (Residues: 335-458; Coverage: 26%)
Gene names: Etv6, Tel, Tel1
Sequence domains: Ets-domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: simulated annealing
Chemical shifts: BMR17742  
Expression system: Escherichia coli BL21(DE3)