› 2ldu

Solution NMR

Solution NMR Structure of Heat shock factor protein 1 DNA binding domain from homo sapiens, Northeast Structural Genomics Consortium Target HR3023C

Released:
DOI: 10.2210/pdb2ldu/pdb
PDB entry 2ldu coloured by chain, ensemble of 20 models, front view.
PDB entry 2ldu coloured by chain, ensemble of 20 models, side view.
PDB entry 2ldu coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Liu G, Xiao R, Ciccosanti C, Janjua H, Acton TB, Lee H, Wang HB, Huang YB, Everett JK, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169459 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heat shock factor protein 1 Chain: A
Molecule details ›
Chain: A
Length: 125 amino acids
Theoretical weight: 14.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q00613 (Residues: 10-123; Coverage: 22%)
Gene names: HSF1, HSTF1
Sequence domains: HSF-type DNA-binding
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: distance geometry, molecular dynamics, simulated annealing, torsion angle dynamics
Expression system: Escherichia coli

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