› 2l88

Solution NMR

Solution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequence

Released:
DOI: 10.2210/pdb2l88/pdb
PDB entry 2l88 coloured by chain, ensemble of 10 models, front view.
PDB entry 2l88 coloured by chain, ensemble of 10 models, side view.
PDB entry 2l88 coloured by chain, ensemble of 10 models, top view.
Source organism: synthetic construct
Primary publication:
Solution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequence.
Tong X, Lan W, Zhang X, Wu H, Liu M, Cao C
Nucleic Acids Res 39 6753-63 (2011)
PMID: 21540209

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115524 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3' Chain: A
Molecule details ›
Chain: A
Length: 20 nucleotides
Theoretical weight: 6.39 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 50%
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Not provided

Quick links

Citations

8 review citations

NMR spectroscopy of G-quadruplexes.
Adrian et al. (2012)
7 more

1 mention without citation

Solution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequence.
Tong et al. (2011)