› 2l76

Solution NMR

Solution NMR structure of human NFATC2IP ubiquitin-like domain, NFATC2IP_244_338, NESG target HT65A/OCSP target hs00387_244_338/SGC-toronto

Released:
DOI: 10.2210/pdb2l76/pdb
PDB entry 2l76 coloured by chain, ensemble of 20 models, front view.
PDB entry 2l76 coloured by chain, ensemble of 20 models, side view.
PDB entry 2l76 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Wu B, Yee A, Houliston S, Doherty R, Semesi A, Dhe-Paganon S, Arrowsmith CH, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185487 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NFATC2-interacting protein Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NCF5 (Residues: 244-338; Coverage: 23%)
Gene names: NFATC2IP, NIP45
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: simulated annealing
Expression system: Escherichia coli

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