› 2l5c

Solution NMR

Solution structures of human PIWI-like 1 PAZ domain

Released:
DOI: 10.2210/pdb2l5c/pdb
PDB entry 2l5c coloured by chain, ensemble of 20 models, front view.
PDB entry 2l5c coloured by chain, ensemble of 20 models, side view.
PDB entry 2l5c coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain.
Zeng L, Zhang Q, Yan K, Zhou MM
Proteins 79 2004-9 (2011)
PMID: 21465557

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188562 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Piwi-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96J94 (Residues: 266-399; Coverage: 16%)
Gene names: HIWI, PIWIL1
Sequence domains: PAZ domain
Structure domains: paz domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DGSA-distance geometry simulated annealing, torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

PIWI-interacting RNAs: small RNAs with big functions.
Ozata et al. (2019)
2 more

2 mentions without citation

Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain.
Zeng et al. (2011)
1 more