› › Structure analysis

NMR Structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of EKLF

Solution NMR
PDB entry 2l2i coloured by chain, ensemble of 20 models, front view.
PDB entry 2l2i coloured by chain, ensemble of 20 models, side view.
PDB entry 2l2i coloured by chain, ensemble of 20 models, top view.
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: General transcription and DNA repair factor IIH subunit TFB1 and Krueppel-like factor 1
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 9049.81 Å2
Buried surface area: 1450.92 Å2
Dissociation area: 725.46 Å2
Dissociation energy (ΔGdiss): 1.92 kcal/mol
Dissociation entropy (TΔSdiss): 9.65 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-152447

Macromolecules

General transcription and DNA repair factor IIH subunit TFB1
Chain: A
Length: 115 amino acids
Theoretical weight: 12.9 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P32776 (Residues: 2-115; Coverage: 18%)
Gene names: D9740.3, TFB1, YDR311W
Pfam: TFIIH p62 subunit, N-terminal domain
InterPro:
CATH: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
General transcription and DNA repair factor IIH subunit TFB1 in PDB entry 2l2i, assembly 1, front view.
General transcription and DNA repair factor IIH subunit TFB1 in PDB entry 2l2i, assembly 1, side view.
General transcription and DNA repair factor IIH subunit TFB1 in PDB entry 2l2i, assembly 1, top view.
Molecule details ›

Search similar proteins

Krueppel-like factor 1
Chain: B
Length: 42 amino acids
Theoretical weight: 4.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13351 (Residues: 51-90; Coverage: 11%)
Gene names: EKLF, KLF1
Pfam: Erythroid krueppel-like transcription factor, transactivation 2
InterPro: Krueppel-like factor 1, transactivation domain 2
Krueppel-like factor 1 in PDB entry 2l2i, assembly 1, front view.
Krueppel-like factor 1 in PDB entry 2l2i, assembly 1, side view.
Krueppel-like factor 1 in PDB entry 2l2i, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links