2l11

Solution NMR

Solution NMR structure of the Cbx3 in complex with H3K9me3 peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Chromobox protein homolog 3 Chain: A
Molecule details ›
Chain: A
Length: 54 amino acids
Theoretical weight: 6.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13185 (Residues: 29-81; Coverage: 29%)
Gene name: CBX3
Sequence domains: Chromo (CHRromatin Organisation MOdifier) domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Histone H3.2 Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.61 KDa
Source organism: Xenopus laevis
Expression system: Not provided
UniProt:
  • Canonical: P84233 (Residues: 2-16; Coverage: 11%)

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: molecular dynamics
Chemical shifts: BMR17071  
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided