Function and Biology

Solution structure of the complex of ubiquitin and the VHS domain of Stam2

Source organism: Homo sapiens
Biochemical function: ubiquitin binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00790
Domain description: VHS domain
Occurring in:
  1. Signal transducing adapter molecule 2
The deposited structure of PDB entry 2l0t contains 1 copy of Pfam domain PF00790 (VHS domain) in Signal transducing adapter molecule 2. Showing 1 copy in chain B.

PF00240
Domain description: Ubiquitin family
Occurring in:
  1. Ubiquitin
The deposited structure of PDB entry 2l0t contains 1 copy of Pfam domain PF00240 (Ubiquitin family) in Ubiquitin. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002014
Domain description: VHS domain
Occurring in:
  1. Signal transducing adapter molecule 2
IPR019956
Domain description: Ubiquitin domain
Occurring in:
  1. Ubiquitin
IPR000626
Domain description: Ubiquitin-like domain
Occurring in:
  1. Ubiquitin
IPR008942
Domain description: ENTH/VHS
Occurring in:
  1. Signal transducing adapter molecule 2
IPR047493
Domain description: STAM2, VHS domain
Occurring in:
  1. Signal transducing adapter molecule 2
IPR019954
Domain description: Ubiquitin conserved site
Occurring in:
  1. Ubiquitin
IPR029071
Domain description: Ubiquitin-like domain superfamily
Occurring in:
  1. Ubiquitin

Structure domains

CATH CATH domains
1.25.40.90
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Occurring in:
  1. Signal transducing adapter molecule 2
The deposited structure of PDB entry 2l0t contains 1 copy of CATH domain 1.25.40.90 (Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat) in Signal transducing adapter molecule 2. Showing 1 copy in chain B.
3.10.20.90
Class: Alpha Beta
Architecture: Roll
Topology: Ubiquitin-like (UB roll)
Homology: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Occurring in:
  1. Ubiquitin
The deposited structure of PDB entry 2l0t contains 1 copy of CATH domain 3.10.20.90 (Ubiquitin-like (UB roll)) in Ubiquitin. Showing 1 copy in chain A.