2kwi

Solution NMR

RalB-RLIP76 (RalBP1) complex

Released:

Function and Biology Details

Reactions catalysed:
GTP + H(2)O = GDP + phosphate
ATP + H(2)O + xenobiotic(Side 1) = ADP + phosphate + xenobiotic(Side 2)
ATP + H(2)O + glutathione-S-conjugate(Side 1) = ADP + phosphate + glutathione-S-conjugate(Side 2)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ras-related protein Ral-B Chain: A
Molecule details ›
Chain: A
Length: 178 amino acids
Theoretical weight: 20.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11234 (Residues: 8-185; Coverage: 86%)
Gene name: RALB
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
RalA-binding protein 1 Chain: B
Molecule details ›
Chain: B
Length: 56 amino acids
Theoretical weight: 6.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15311 (Residues: 393-446; Coverage: 8%)
Gene names: RALBP1, RLIP, RLIP1, RLIP76
Structure domains: Methane Monooxygenase Hydroxylase; Chain G, domain 1

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli