Solution NMR

Mechanism for the selective interaction of C-terminal EH-domain proteins with specific NPF-containing partners


Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
EH domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 11.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9H4M9 (Residues: 435-534; Coverage: 19%)
Gene names: CDABP0131, EHD1, PAST, PAST1
Sequence domains: Cytoskeletal-regulatory complex EF hand
Structure domains: EF-hand
MICAL-like protein 1 Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.86 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q8N3F8 (Residues: 419-433; Coverage: 2%)
Gene names: KIAA1668, MICALL1, MIRAB13

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: simulated annealing
Chemical shifts: BMR16671  
Expression systems:
  • Escherichia coli
  • Not provided