Solution NMR

NMR solution structure of Lamin-B1 protein from Homo sapiens: Northeast Structural Genomics Consortium MEGA target, HR5546A (439-549)

Source organism: Homo sapiens
Entry authors: Swapna GVT, Ciccosanti CL, Belote R, Hamilton K, Acton T, Huang Y, Xiao R, Everett J, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Lamin-B1 Chain: A
Molecule details ›
Chain: A
Length: 122 amino acids
Theoretical weight: 13.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P20700 (Residues: 439-549; Coverage: 19%)
Gene names: LMN2, LMNB, LMNB1
Structure domains: Lamin Tail domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: simulated annealing
Chemical shifts: BMR16572  
Expression system: Escherichia coli BL21(DE3)