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Solution NMR

NMR solution structure of Lamin-B1 protein from Homo sapiens: Northeast Structural Genomics Consortium MEGA target, HR5546A (439-549)

Released:
DOI: 10.2210/pdb2kpw/pdb
PDB 2kpw coloured by chain and viewed from the front.
PDB 2kpw coloured by chain and viewed from the side.
PDB 2kpw coloured by chain and viewed from the top.
Source organism: Homo sapiens
Entry authors: Swapna GVT, Ciccosanti CL, Belote R, Hamilton K, Acton T, Huang Y, Xiao R, Everett J, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lamin-B1 Chain: A
Molecule details ›
Chain: A
Length: 122 amino acids
Theoretical weight: 13.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P20700 (Residues: 439-549; Coverage: 19%)
Gene names: LMN2, LMNB, LMNB1
Structure domains: Lamin Tail domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: simulated annealing
Chemical shifts: BMR16572  
Expression system: Escherichia coli BL21(DE3)

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