› 2kp3

Solution NMR

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196423 (preferred)
Entry contents:
2 distinct RNA molecules
Macromolecules (2 distinct):
RNA (5'-R(*(GAO)P*(CAR)P*(UAR)P*(A5O)P*(UAR)P*(A5O)P*(A5O)P*(UAR)P*(GAO)P*(GAO))-3') Chain: A
Molecule details ›
Chain: A
Length: 10 nucleotides
Theoretical weight: 3.2 KDa
Source organism: Synthetic construct
Expression system: Not provided
RNA (5'-R(*CP*CP*AP*UP*UP*AP*UP*AP*GP*C)-3') Chain: B
Molecule details ›
Chain: B
Length: 10 nucleotides
Theoretical weight: 3.12 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
4 modified residues:
Ligand GAO 3 x GAO
Ligand CAR 1 x CAR
Ligand UAR 3 x UAR
Ligand A5O 3 x A5O

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics, matrix relaxation
Expression system: Not provided

Quick links

Citations

4 review citations

Designing chemically modified oligonucleotides for targeted gene silencing.
Deleavey et al. (2012)
3 more

4 mentions without citation

The structural diversity of artificial genetic polymers.
Anosova et al. (2016)
3 more