› 2koc

Solution NMR

NMR solution structure of a 14-mer hairpin RNA with cUUCGg tetraloop

Released:
DOI: 10.2210/pdb2koc/pdb
PDB entry 2koc coloured by chain, ensemble of 20 models, front view.
PDB entry 2koc coloured by chain, ensemble of 20 models, side view.
PDB entry 2koc coloured by chain, ensemble of 20 models, top view.
Source organism: Synthetic construct
Primary publication:
High-resolution NMR structure of an RNA model system: the 14-mer cUUCGg tetraloop hairpin RNA.
Nozinovic S, Fürtig B, Jonker HR, Richter C, Schwalbe H
Nucleic Acids Res 38 683-94 (2010)
PMID: 19906714

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196422 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (5'-R(P*GP*GP*CP*AP*CP*UP*UP*CP*GP*GP*UP*GP*CP*C)-3') Chain: A
Molecule details ›
Chain: A
Length: 14 nucleotides
Theoretical weight: 4.45 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Not provided

Quick links

Citations

10 review citations

High-resolution reversible folding of hyperstable RNA tetraloops using molecular dynamics simulations.
Chen et al. (2013)
9 more

40 mentions without citation

RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.
Šponer et al. (2018)
39 more