PDBe 2khu

Solution NMR

Solution Structure of the Ubiquitin-Binding Motif of Human Polymerase Iota

Released:

Function and Biology Details

Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA polymerase iota; Immunoglobulin G-binding protein G Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 12.35 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P19909 (Residues: 304-359; Coverage: 10%)
  • Canonical: Q9UNA4 (Residues: 699-740; Coverage: 6%)
Gene names: POLI, RAD30B, spg

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 95%
Refinement method: simulated annealing
Chemical shifts: BMR16882  
Expression system: Escherichia coli